Lipid Bilayer Simulations of CXCR4 with Inverse Agonists and Weak Partial Agonists
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چکیده
منابع مشابه
Lipid bilayer simulations of CXCR4 with inverse agonists and weak partial agonists.
CXCR4 is a G protein-coupled receptor (GPCR) that has multiple critical functions in normal and pathologic physiology that include regulation of the metastatic behavior of mammary carcinoma, and utilization as a coreceptor for infection by T-tropic strains of human immunodeficiency virus-1. Molecular dynamic simulations of the rhodopsin-based homology model of CXCR4 were performed in a solvated...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m307850200